Experimental Canine Coronary Atherosclerosis
نویسندگان
چکیده
منابع مشابه
Protein-lipid relationships in experimental canine atherosclerosis.
The applicability of Cohn's method number 10 to the study of dog plasma has made possible this investigation of experimental canine atherosclerosis. Administration of thiouracil which causes hypercholesterolemia but no atherosclerosis in dogs produces no considerable alteration in the distribution of plasma lipoproteins. High cholesterol feeding and administration of thiouracil causes both athe...
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• The first experimental evidence that cholesterol is an atherogenic factor was presented by Anitschkovv and Chalatow. Rittenberg and Schoenheimer's demonstration that animals can synthesize cholesterol, and other investigationswhich show that dietary fat can effectively influence serum cholesterol levels in man, focused attention on dietary lipids other than cholesterol in atherogenesis. Exper...
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Characterization of the hyperlipoproteinemia induced by feeding high-cholesterol diets to hypothyroid dogs was undertaken in an attempt to identify a lipoprotein pattern or a specific lipoprotein responsible for the atherosclerosis associated with such hyperlipoproteinemia. Various degrees of hyperlipidemia and atherosclerosis were produced during the diet, which was imposed for 3 months to mor...
متن کاملCoronary blood flow in experimental canine left ventricular hypertrophy.
To determine whether left ventricular hypertrophy [LVH] altered total and regional coronary blood flow, we inflated a balloon around the ascending aorta of nine dogs; six acute and six sham-operated dogs were controls. After 6 weeks, all dogs were studied with an open chest under anesthesia; the balloons were deflated. There was moderate LVH as shown by increased left ventricular weight and fib...
متن کاملAn Experimental Model for Studying Atherosclerosis
The aim of the present study was to clarify if old N-MRI rat, a strain which is easily available in Iran and cheap to maintain, is a suitable alternative to those previously reported. In this model, we compared three quantifiable parameters between old and young rats: biochemically, involving measurement of differences in the lipid profile. Histologically, the differences of the thickness of th...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1973
ISSN: 0003-4932
DOI: 10.1097/00000658-197303000-00019